Which herbal supplement is commonly used for mild to moderate depression?

St. John's wort is recognized for its potential effectiveness in treating mild to moderate depression. This herbal supplement has been widely studied, and its active components, particularly hypericin and hyperforin, are thought to influence neurotransmitter activity in the brain, specifically serotonin, which plays a significant role in mood regulation. Many clinical trials have shown that St. John's wort can be as effective as certain conventional antidepressants, but typically with fewer side effects.

The other herbs mentioned do not have the same established link to depression treatment. For instance, saw palmetto is primarily used for prostate health, ginkgo biloba is often taken to improve cognitive function and memory, and garlic is widely recognized for its potential cardiovascular benefits. While these supplements possess various health benefits, none are specifically indicated for addressing mild to moderate depression like St. John's wort.