Self-Evaluation Examination (SEE) Practice Exam

Cryoprecipitate is a blood product that is rich in clotting factors, specifically derived from plasma. It is primarily composed of fibrinogen, factor VIII, factor XIII, and von Willebrand factor.

The reason why the presence of both factor VIII and fibrinogen is associated with cryoprecipitate is due to their critical roles in the coagulation process. Fibrinogen is essential for the formation of fibrin, the protein that forms the basis of a blood clot. Factor VIII, on the other hand, is vital for amplifying the coagulation cascade and is particularly crucial in the context of hemophilia A, where its deficiency leads to bleeding disorders.

While von Willebrand factor is important for platelet adhesion and is present in cryoprecipitate, the specific combination of factor VIII and fibrinogen is more directly associated with the therapeutic uses of cryoprecipitate, such as in treating patients with bleeding disorders or those requiring surgical interventions.

The other choices either mention factors that are not relevant to the primary composition of cryoprecipitate or exclude critical components. This emphasizes the important role of factor VIII and fibrinogen in clot formation, making them the key factors associated with cryop