Selective stimulation of the β2-receptor primarily results in which of the following?

Selective stimulation of the β2-receptor primarily promotes increased insulin secretion. β2-receptors, which are primarily found in the pancreas and various other tissues, have several physiological effects when activated. In the context of the pancreas, stimulation of β2-receptors enhances insulin secretion from the β-cells. This effect is significant because it plays a critical role in regulating glucose metabolism and maintaining energy homeostasis.

By promoting insulin release, β2-receptor stimulation helps lower blood sugar levels, which is particularly relevant in situations such as exercise or stress, where the body requires a rapid increase in glucose availability for energy. Additionally, the action of β2-receptors is also associated with transporting glucose into cells, further emphasizing their importance in metabolic processes.

In contrast, increased heart rate is primarily mediated by β1-receptors, while pupillary constriction is associated with muscarinic receptors, and detrusor muscle contraction is influenced by parasympathetic activation. Thus, the primary roles of the β2-receptor align closely with enhancing insulin secretion, demonstrating its significance in metabolic regulation.