How does succinylcholine affect intraocular pressure?

Succinylcholine is a depolarizing neuromuscular blocker commonly used in anesthesia. One of the notable effects of succinylcholine is that it can increase intraocular pressure, which is crucial for considerations during procedures involving patients with eye conditions or those at risk for increased intraocular pressure.

The mechanism behind this increase involves the muscle contractions that succinylcholine induces. When the drug causes fasciculations (involuntary muscle contractions) in the muscles around the eye, it can lead to an increase in the pressure within the eye. This is particularly relevant during intubation or other procedures that require rapid sedation or paralysis, making it important for practitioners to be aware of this effect, especially in patients with glaucoma or other ocular issues.

Understanding this effect of succinylcholine is critical in clinical settings, as it can influence the choice of muscle relaxants or dictate the management of intraocular pressure in susceptible patients.